PCIe NVMe SSD on PCIe slot-Worth it?

m 2 pcie 4 0 in 3 0 slot
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NVMe SSDs, including the KC3000 PCIe , the NV2 for smaller form factor devices and the DC1500M four-lane PCIe for mixed workloads Toshiba

I have an AMD 5800x, which has 20 pcie lanes I want to put 2 GPUs in a motherboard with 2 PCIe x16 slots, but 1 of

m2 pcie slot PCIe PCIe x 16 Slots 7 · 6 · 5 · 4 · 3 · 2 · 1 SSD Slots 5 x Ultra-Fast Storage：4*PCIe x4 slots; Efficient Overall Thermal：VRM Thermal

m2 slot types You're referring to NVME based M2 SSDs, correct? But yes if the SSD is PCIE spec then of course the speed will be less when used on PCIE